Electrophysiological Generalisation of Secondary Generalized TonicClonic Seizure
The International League Against Epilepsy (ILAE) has classified seizures since 1964. Generalized tonic-clonic seizures are characterized by a sudden uncontrolled electrical disturbance of the brain. They are accompanied by focal involuntary movements, convulsions, and altered consciousness.
These seizures can be distinguished by the presence of epileptiform activity, which is defined as the presence of an Si(t) above 2.5. However, the extent of this activity is uncertain. Child Seizure Detection Moreover, non-invasive EEG recording may not record the full extent of epileptiform activity.
A 25-year-old Burmese man had a focal seizure. He was unconscious for approximately 30 seconds. After he regained consciousness, he developed a right-sided clonus. His underlying medical history included thalassemia.
To diagnose the patient, intracranial EEG recordings were examined for signs of epileptiform activity. This was done using a machine learning algorithm that was FDA-cleared.
The study investigated electrophysiological generalisation in secondarily generalised tonic-clonic seizures. Seventy-two patients were recruited. All patients gave their consent for scientific analysis.
The results of the study suggest that secondarily generalised tonic-clonic seizure may be electrophysiologically generalised. However, it is important to point out that in humans, cortical areas will never be fully sampled by intracranial electrodes.
Seizures of the secondary generalized type can be detected with wrist accelerometers. A patient is evaluated for symptoms of the event, actions performed during the event, and responses to interventions.
Specifically, the patient is informed of potential risk factors in the environment. They are encouraged to make lifestyle changes, such as exercising, taking anti-parasite medications, and eating healthy foods. They also verbalize their understanding of the disorder, the effects of the seizure, and the actions they take to minimize their risk.
