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How is Mesothelioma Treated?

Mesothelioma patients experience many symptoms, based on the location where the tumors develop. The symptoms usually take time to develop and can be mistaken for common illnesses such as pneumonia or the flu.

Doctors diagnose mesothelioma through testing for imaging and blood tests. They also remove any excess fluid that has accumulated around the lungs through a procedure known as thoracentesis.

Surgery

Surgeons remove mesothelioma tumors when possible to lessen symptoms and improve a patient's overall quality of life. Surgery can also aid doctors to determine if a patient has mesothelioma or to detect smaller tumors. Mesothelioma surgeons are trained to remove the affected tissue without damaging healthy tissues, organs or nerves.

The options for mesothelioma surgery differ depending on the type of cancer and cancer stage. A doctor will consider the patient's health, age and other factors when determining the best surgical approach.

Pleurectomy, extrapleural pneumonectomy, and pleurodesis are all surgical procedures to treat mesothelioma. Each mesothelioma treatment has its own benefits and risks. A skilled mesothelioma doctor can provide information about every option and suggest the best surgical procedure for you.

A pleurectomy and decortication (P/D) mesothelioma operation is a less extensive surgery than an extrapleural pneumonectomy, or EPP. In P/D, surgeons remove the lining of the lung and any visible tumours. They do not take out the diaphragm or lung. This surgery is an excellent mesothelioma treatment option for patients who wish to preserve their health and avoid the risks associated with removing both lung.

P/D surgery is usually coupled with hyperthermic intra-thoracic chemotherapy which involves adding chemotherapy drugs that are heated to fight cancer to a solution of saltwater and delivers them directly into the chest cavity. This reduces the amount of time a patient spends in hospital and allows patients to receive multiple treatments faster.

Pleural mesothelioma is a common cause of excessive fluid to build up in the lungs, or the pleural effusion. mesothelioma treatment options can lead to breathing problems and chest pain. The fluid can be removed by a doctor using an operation that is minimally invasive, known as a Thoracentesis. In this procedure, an instrument is inserted into the chest to draw out fluid.

A pyeloplasty is an additional surgical option to treat mesothelioma pleural. During the procedure, doctors insert tubes into the abdomen to allow fluid to be constantly drained. This can ease symptoms like nausea and abdominal pain, fever and breathing problems. The tube can be removed after the volume of fluid has decreased significantly.

Chemotherapy

The kind of treatment you receive depends on a variety of variables, including the stage of mesothelioma (the extent of it) as well as whether doctors believe your tumor can be surgically removed, and your overall health. You might be able to take part in a clinical trial which evaluates a novel drug combination or test.





Radiotherapy, chemotherapy and surgery are the most common treatments. These treatments can alleviate the symptoms of mesothelioma, but will not eliminate it.

Mesothelioma chemotherapy drugs are used to kill cancer cells and stop them from growing. They are usually administered intravenously or via injection into the vein. Patients receive them in a series, each followed by a period of rest to allow the body to recuperate. Pemetrexed and cisplatin as well as other chemotherapies are among the most common ones used to treat mesothelioma.

In the case of pleural mesothelioma, chemotherapy is often administered prior to surgery to shrink the tumors and make the operation less demanding. Neoadjuvant treatment is what this is called. After surgery, it can also be used to eliminate microscopic cancerous cells which are not visible to the eye. This is known as adjuvant therapy.

The use of radiation therapy is often used to treat pleural melanoma, and it is delivered in different ways. Doctors can opt for traditional photon or proton radiation. They can also use intensity-modulated radiation therapy or IMRT to limit healthy tissue damage and increase the doses of irradiation.

Doctors can administer chemotherapy drugs such as the combination of pemetrexed and cisplatin by an intravenous catheter through the abdomen to treat the peritoneal msothelioma. They can also administer it by pump into the peritoneal cavity through an instrument known as a catheter.

The side effects may be mild or severe, but they can be managed by medications and support services. The severity of side effects can vary. It is crucial to report any symptoms to your medical team. A recent study found that women suffer more adverse reactions from mesothelioma treatments than men. Researchers aren't able to pinpoint the reason. Researchers suggest that this could be due to the fact that women tend to seek medical care more often when sick and tell their doctor what symptoms they're experiencing.

Radiation Therapy

Mesothelioma treatments focus on relieving symptoms and improving quality of life, however they are not always able to cure the disease. It's important to talk about your goals with your healthcare team before treatment starts. Some patients are determined to do everything possible to increase their chances of a cure, while others prefer a plan of treatment that makes them as comfortable as they can during the time remaining.

Surgery is usually part of any mesothelioma therapy plan. Doctors remove cancerous tissue to alleviate symptoms and prolong the duration of the life expectancy. There are three types of mesothelioma surgeries:

Pleurectomy/Decortication (P/D) removes the pleura, or lining around the lungs. The procedure also removes any visible tumours in the chest cavity. Extrapleural Pneumonectomy eliminates the entire diaphragm and lungs.

Radiation therapy uses x ray beams to kill the cells of mesothelioma. The procedure is painless and noninvasive. Doctors can utilize a method called Intensity-Modulated Radiotherapy (IMRT) that is a method where the radiation beams are modified to target cancerous cells more effectively, without affecting healthy tissue.

Although mesothelioma cannot be cured by radiation alone however, it can help reduce tumor size before surgery or kill remaining cancer cells that were not removed during the operation. It is a method to ease discomfort and pain for patients with late-stage cancer.

Mesothelioma is a type of cancer that develops quickly and responds better to radiotherapy than slower-growing tumors. Radiation damages the DNA of cancerous cells and kills them within days, weeks or months. A doctor can adjust the duration of a radiation session to accommodate each patient's specific needs.

Even with the most effective cancer treatments the risk of side effects is common. Weight loss, fatigue, and nausea are among the most common side-effects. Most of these adverse effects can be managed and controlled by medication.

Immunotherapy

Immunotherapy drugs stimulate your body's natural defenses to fight cancer cells. They are usually given as intravenous infusions (IV) and can be combined with another treatment. Certain studies have proven that immunotherapy can improve survival times for people with the pleural msothelioma. This is when it is combined with chemotherapy or radiotherapy.

Mesothelioma specialists can determine if you have the disease through a physical exam and ordering imaging tests such as X-rays and CT scans. They may also want to conduct a biopsy, which is where they take a small amount of tissue to test for lab tests. The results of your biopsy and other tests can help your doctor plan the treatment.

Most doctors treat mesothelioma based on the location of the cancer and whether it has spread. You might want to get rid of any cancer or lessen symptoms to prolong your life. Your doctor will create the treatment plan which could include surgery, chemo and radiation therapy. Many doctors combine these treatments into a multimodal treatment plan.

The mesothelioma surgery procedure can remove cancerous tissue, shrink tumors and relieve symptoms. Not everyone with mesothelioma is capable of undergoing surgery. Some patients with mesothelioma of the peritoneal region or pleural tumor suffer from scarring that hinders surgeons from accessing the cancerous tissue. These patients are best treated by targeted therapy or immunotherapy.

Targeted therapy limits a cancer's growth by denying it of oxygen or reducing its cell division. Avastin, also referred to as bevacizumab, is one type of targeted treatment used to treat mesothelioma. It is given via IV infusions every couple of weeks.

Mesothelioma immunotherapy assists your immune system identify mesothelioma cancer cells and destroy them. It works by blocking proteins that could hinder your immune system from recognizing mesothelioma tumor cells. Two mesothelioma immunotherapy options are nivolumab and pembrolizumab.

Treatment options can improve the quality of life and allow people to live longer when they suffer from the majority of mesothelioma. Talk to your mesothelioma specialist about the various treatment options available to you and what the pros and cons for each. Discuss your goals with your care team as well.